Role of mitochondrial dysfunction in degenerative brain diseases, an overview

HIGHLIGHTS

• who: Ruben K. Dagda from the DepartmentUniversity of have published the article: Role of Mitochondrial Dysfunction in Degenerative Brain Diseases, an Overview, in the Journal: (JOURNAL) of 12/09/2018
• future: These published observations warrant future research to analyze how MFF and mitophagy regulators interplay with other brain degenerative disease-linked proteins to govern mitochondrial structure/function and mitophagy.

SUMMARY

Unlike proliferating cells, neurons predominantly rely on oxidative_phosphorylation to thrive and establish neuronal networks. Indeed, the high reliance of neurons on oxidative_phosphorylation is evident as mitochondrial dysfunction underlies the etiology of . . .

 



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