Role of mitochondrial translation in remodeling of energy metabolism in er/pr(+) breast cancer

HIGHLIGHTS

  • who: Emine C. Koc from the University of Salford, United Kingdom have published the Article: Role of mitochondrial translation in remodeling of energy metabolism in ER/PR(+) breast cancer, in the Journal: (JOURNAL)
  • what: The authors investigated the changes in the expression of OXPHOS subunits and MRPs responsible for the synthesis of 13 mtencoded subunits in 26 ER/PR(+) biopsies.
  • how: The agreement between the data from the breast cancer CPTAC proteomics analyses and the immunoblotting studies imply that the reduced steady-state expression of complex I and subunits in breast cancer luminal . . .

     

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