Role of mitochondrial transporters on metabolic rewiring of pancreatic adenocarcinoma: a comprehensive review

HIGHLIGHTS

  • who: Graziantonio Lauria and collaborators from the Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, Italy have published the article: Role of Mitochondrial Transporters on Metabolic Rewiring of Pancreatic Adenocarcinoma: A Comprehensive Review, in the Journal: Cancers 2023, 15, 411. of /2023/
  • what: The aim of this review is to comprehensively evaluate the current experimental evidence about the function of these carriers in metabolic rewiring. In this regard, the study showed that UCP2 deletion induced a metabolic reprogramming in which glucose-derived pyruvate was directed to fatty_acid synthesis by increasing the synthesis . . .

     

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