HIGHLIGHTS
- who: Shu-Hong Huang and Zhaoqiang Zhang from the Danube Private University, Austria have published the Article: Role of mitophagy in the neurodegenerative diseases and its pharmacological advances: A review, in the Journal: (JOURNAL)
SUMMARY
Previous research suggests that TBK1 improves the cargo adapter binding affinity to ubiquitin chains by phosphorylation and enhances mitophagy (Pickles et_al, 2018). oxygen species (ROS) (Ashrafi and Schwarz, 2013; Hirota et_al, 2015; Chen et_al, 2020). This results in continuous accumulation of damaged mitochondria, and may even cause neuronal defects, thereby inducing Alzheimer`s disease (AD), Parkinson`s disease . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.