Role of pannexin-1-p2x7r signaling on cell death and pro-inflammatory mediator expression induced by clostridioides difficile toxins in enteric glia

HIGHLIGHTS

• who: Andrea V. Loureiro from the Washington University in StLouis, United States have published the paper: Role of Pannexin-1-P2X7R signaling on cell death and pro-inflammatory mediator expression induced by Clostridioides difficile toxins in enteric glia, in the Journal: (JOURNAL)
• what: Due to the higher deleterious effects of C. difficile toxins occurred on the later time point, the authors focused on 18h incubation time, as shown by others . The authors demonstrated that Panx1 is involved in caspase 3/7 activation and in phosphatidylserine (PS) exposure.
• how: Student`s t test or . . .
  

   

  

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