Role of ptpn22 and csk gene polymorphisms as predictors of susceptibility and clinical heterogeneity in patients with henoch-schönlein purpura (iga vasculitis)

HIGHLIGHTS

  • who: Raquel López-Mejías from the (UNIVERSITY) have published the article: Role of PTPN22 and CSK gene polymorphisms as predictors of susceptibility and clinical heterogeneity in patients with Henoch-Schönlein purpura (IgA vasculitis), in the Journal: (JOURNAL)
  • what: This study had >80 % of power to detect genotypic OR >1.4 for CSK rs34933034, CSK rs1378942, PTPN22 rs2476601 (R620W) and PTPN22 rs33996649 (R263Q).
  • how: The authors analyzed two well- known CSK (CSK rs34933034 and CSK rs1378942) and two functional PTPN22 (PTPN22 rs2476601 (R620W) and PTPN22 rs33996649 (R263Q)) polymorphisms previously associated with . . .

     

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