Role of selective histone deacetylase 6 inhibitor acy-1215 in cancer and other human diseases

HIGHLIGHTS

  • who: Jianglei Li and collaborators from the Department of Gastroenterology, The Second Xiangya Hospital of Central South University, Changsha, China, Research Center have published the Article: Role of Selective Histone Deacetylase 6 Inhibitor ACY-1215 in Cancer and Other Human Diseases, in the Journal: (JOURNAL) of March/17,/2014

SUMMARY

    To develop potentially less toxic and more effective treatments, studies on selective HDACs inhibitors are gradually deepening (Zhao et_al, 2021; He et_al, 2020). A series of compounds containing urea-based branched linkers with hydroxamate as ZBG have been identified as selective HDAC6 inhibitors . . .

     

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