Role of the c-terminal extension of formin 2 in its activation by spire protein and processive assembly of actin filaments*

HIGHLIGHTS

  • who: Pierre Montaville from the (UNIVERSITY) have published the article: Role of the C-terminal Extension of Formin 2 in Its Activation by Spire Protein and Processive Assembly of Actin Filaments*, in the Journal: (JOURNAL) of February/12,/2016
  • what: To integrate the results in the processive cycle of open to closed configurations of FH2 bound to growing barbed ends , the authors propose that FSI assists the transition toward the open configuration as follows.

SUMMARY

    This direct interaction is required for the synergy between the two proteins in actin assembly. The . . .

     

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