Role of the constitutive splicing factors u2af65 and sap49 in suboptimal rna splicing of novel retroviral mutants*

HIGHLIGHTS

• who: John Bouck from the (UNIVERSITY) have published the Article: Role of the Constitutive Splicing Factors U2AF65 and SAP49 in Suboptimal RNA Splicing of Novel Retroviral Mutants*, in the Journal: (JOURNAL) of January/22,/1998
• what: In this report, the authors show that a mutant blocked at step 1 fails to form a stable spliceosomal complex, whereas one blocked at step 2 shows a defect in its ability to transit through the last spliceosomal complex. Using UV cross-linking methods, the authors show that regulation at each step is associated with specific changes in the . . .
  

   

  

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