Role of the tuberous sclerosis gene-2 product in cell cycle control

HIGHLIGHTS

  • who: Thomas Soucek from the (UNIVERSITY) have published the research: Role of the Tuberous Sclerosis Gene-2 Product in Cell Cycle Control, in the Journal: (JOURNAL) of April/28,/1997
  • what: The authors investigated the role of TSC2 in the regulation of the eukaryotic cell cycle. The authors report, using antisense oligonucleotides, that reducing the expression of the TSC2 product tuberin has profound effects on the cell cycle.

SUMMARY

    The TSC2 gene on chromosome 16 encodes a 1784-amino_acid tumor suppressor protein, tuberin, that functions as a GTPase-activating protein for . . .

     

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