Role of the tumor microenvironment in regulating pancreatic cancer therapy resistance

HIGHLIGHTS

  • who: Daiyong Deng et al. from the Center for Cell Signaling, Rutgers New Jersey Medical School, Newark, NJ, USA have published the article: Role of the Tumor Microenvironment in Regulating Pancreatic Cancer Therapy Resistance, in the Journal: Cells 2022, 11, 2952. of /2022/
  • what: The authors focus on the interplay between cancer cell and non-cancer cell counterparts that prevents PDAC from apoptosis upon therapeutic treatments.
  • future: Further investigation is required to determine how to sensitize pancreatic tumors to immune checkpoint blockade. In this review the authors summarize therapeutic options for PDAC and . . .

     

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