Role of ubiquitin and sumo in intracellular trafficking

HIGHLIGHTS

  • who: Curr. Issues Mol. Biol. and colleagues from the University of Turku, Turku, Finland have published the article: Role of Ubiquitin and SUMO in Intracellular Trafficking, in the Journal: (JOURNAL)
  • future: SUMOylation has been implicated in the regulation of endocytic processes although when compared to ubiquitin the evidence is less extensive and more work is needed to make general conclusions.

SUMMARY

    Modification is reversible and specific proteases can cleave ubiquitin and SUMO from substrates (Williamson et_al, 2013; Kunz et_al, | Sundvall E1 (Sae1/Aos1-Sae2/Uba2) and E2 (Ubc9) are known to . . .

     

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