HIGHLIGHTS
- who: Stephanie Diaz et al. from the Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette have published the research work: Roles of Cullin-RING Ubiquitin Ligases in Cardiovascular Diseases, in the Journal: Biomolecules 2022, 416 of /2022/
SUMMARY
The signal that triggers such degradation is ubiquitination, a post-translational modification where a chain of the small protein ubiquitin (Ub) is covalently linked to a lysine residue of the target protein. The modular CRL complexes are characterized by a common cullin (CUL) scaffold, a small RING protein (RBX1 or RBX2), and . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.