Rottlerin stimulates exosome/microvesicle release via the increase of ceramide levels mediated by ampk in an in vitro model of intracellular lipid accumulation

HIGHLIGHTS

  • who: Yessenia L. Molina and collaborators from the , Madrid, Spain have published the article: Rottlerin Stimulates Exosome/Microvesicle Release Via the Increase of Ceramide Levels Mediated by Ampk in an In Vitro Model of Intracellular Lipid Accumulation, in the Journal: Biomedicines 2022, 10, 1316. of 19/04/2022
  • what: The authors investigated the effects of rottlerin a polyphenol on secretion in a model of intracellular lipid trafficking impairment and elucidated the mechanism of action. The authors propose that the egress of lipids out of the cell induced by rottlerin ameliorated lipid retention within the endolysosomal . . .

     

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