HIGHLIGHTS
- who: AAVs et al. from the University College London, United Kingdom have published the research work: Routes of administration for adeno-associated viruses carrying gene therapies for brain diseases, in the Journal: (JOURNAL)
- future: Inconsistent results from previous studies may be attributed to various impurities in the viruses and different doses used in each study thus targeting cells via IV injection with rAAV9 is still controversial and further investigation is required to validate these results. It is important in future work to validate these novel AAV vectors in various disease models.
SUMMARY
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