Rpl21 interacts with lamp3 to promote colorectal cancer invasion and metastasis by regulating focal adhesion formation

HIGHLIGHTS

  • who: Jiaxian Zhu from the Department of, Medical University, Xinhu of China have published the paper: RPL21 interacts with LAMP3 to promote colorectal cancer invasion and metastasis by regulating focal adhesion formation, in the Journal: (JOURNAL)
  • what: An orthotopic CRC mouse model was developed to investigate the metastatic ability of CRC. The authors demonstrated that the upregulation of RPL21 promotes the migration and invasion of CRC cells. For the first time, the authors report on the interaction between RPL21 and LAMP3, which regulates the formation of focal adhesions (FAs). The authors focused on RPL21 expression . . .

     

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