Rrbp1 depletion of bone metastatic cancer cells contributes to enhanced expression of the osteoblastic phenotype

HIGHLIGHTS

• who: Rui Chen et al. from the University of Pittsburgh, United States have published the article: RRBP1 depletion of bone metastatic cancer cells contributes to enhanced expression of the osteoblastic phenotype, in the Journal: (JOURNAL)
• what: RRBP1 was the sole shared high-abundance protein involving osteoblast differentiation in CMs from both frontiersin.org 10.3389/fonc.2022.1005152 A B C D E
• how: These results indicated that either MDA-MB231 cell- or PC3 cell-derived RRBP1 suppressed the osteoblastic phenotype expression at least partially by interrupting the BMP2/Smad1/5/9 pathway . . .
  

   

  

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