Rs1h−/y exon 3-del rat model of x-linked retinoschisis with early onset and rapid phenotype is rescued by rs1 supplementation

HIGHLIGHTS

• who: Yong Zeng from the (UNIVERSITY) have published the research: Rs1h−/y exon 3-del rat model of X-linked retinoschisis with early onset and rapid phenotype is rescued by RS1 supplementation, in the Journal: (JOURNAL) of 22/09/2021
• what: The authors report results of creating and characterizing an Rs1h-/y exon3-del rat model using CRISPR/Cas 9 techniques .
• how: In previous pre-clinical safety and toxicity study for a XLRS gene therapy trial the authors used rabbit for some of the studies. Cavity size inner retina thickness outer retina thickness . . .
  

   

  

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