HIGHLIGHTS
- who: Dmytro Havrylyuk from the University of have published the paper: Ru(II) photocages enable precise control over enzyme activity with red light, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
- what: The authors report the successful development of small_molecule inhibitors of CYP1B1 based on a coordination-mediated prodrug strategy. For the light-activated compounds, the experiment was modified as follows: Cells were seeded and grown overnight as described above.
- how: The cellular assay results showed that the inhibitors were cell penetrant.
SUMMARY
Humans express 57 active CYPs, subclassified into . . .
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