Running title: toxicogenetic effect of piperine and capsaicin academy section: cellular

HIGHLIGHTS

  • who: Bioactive compounds et al. from the Soil Analysis Laboratory (LASO) of the Center for Agricultural Sciences (CCA) UFPI, Teresina-PIFor each treatment, the mitotic index (MI, cytotoxicity) and mean chromosomal alteration (genotoxicity) resulting from aneugenic action (metaphase with chromosomal adhesion, metaphase, chromosomal loss, multipolar anaphase, binucleated cells) were evaluated for each treatment among others and/or clastogenic action (chromosomal fragments in metaphase or anaphase, chromosomal bridges and other alterations) (Leme and Marin-Morales, ). Cytotoxicity was also analyzed by the mean value of cells and cells in death process (CDP), which have characteristics such as: heteropicnotic nucleus . . .

     

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