HIGHLIGHTS
- who: Hai-Jia Xu from the Department of Orthopedics, Wuhan Third Hospital, Tongren Hospital of Wuhan University, Wuhan, China have published the article: Runx2 overexpression promotes bone repair of osteonecrosis of the femoral head (ONFH), in the Journal: (JOURNAL)
- what: This research has proved that MSCs overexpressing Runx2 can improve osteogenic genes expression and maintain osteoblastic phenotype, and inhibition of Runx2 would lead to converse results. The authors injected simple MSCs or MSCs that had been transfected with Ad-Runx2 or Runx2-siRNA into ONFH rabbit models, the results showed unsatisfactory results in the Runx2 . . .
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