Ruvbl1-modulated chromatin remodeling alters the transcriptional activity of oncogenic ctnnb1 in uveal melanoma

HIGHLIGHTS

• who: Chao Zhang from the (UNIVERSITY) have published the research: RUVBL1-modulated chromatin remodeling alters the transcriptional activity of oncogenic CTNNB1 in uveal melanoma, in the Journal: (JOURNAL) of 14/Nov/2022
• what: Given the aforementioned evidence and bioinformatics analysis prior to the investigation , RUVBL1 was identified as a potential regulator in chromatin remodeling of UVM, probably depending on transcriptional activity of u03b2-catenin1 (CTNNB1). The study focus was then shifted to whether the functional role of RUVBL1 in UVM progression was achieved by regulating CTNNB1 expression.
• how: The results showed that both . . .
  

   

  

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