Ryr2/irbit regulates insulin gene transcript, insulin content, and secretion in the insulinoma cell line ins-1

HIGHLIGHTS

• who: Kyle E. Harvey from the DepartmentPurdue University have published the Article: RyR2/IRBIT regulates insulin gene transcript, insulin content, and secretion in the insulinoma cell line INS-1, in the Journal: Scientific Reports Scientific Reports
• what: The authors investigated the role of RyR2 in pancreatic u03b2-cell signaling by deleting RyR2 from INS-1 cells using CRISPR-Cas9 gene u00adediting20.
• how: This result is consistent with studies showing that RyR2 is the prominent RyR transcript detected in INS-1 u00adcells5 and human iu00ad slets9.

SUMMARY

The authors further . . .

 



If you want to have access to all the content you need to log in!

Thanks :)

Username or E-mail:

If you don't have an account, you can create one here.