HIGHLIGHTS
- who: Julien Vaubourgeix from the (UNIVERSITY) have published the article: S-Adenosyl-N-decyl-aminoethyl, a Potent Bisubstrate Inhibitor of Mycobacterium tuberculosis Mycolic Acid Methyltransferases, in the Journal: (JOURNAL) of July/17,/2009
SUMMARY
The keto and methoxy groups, with a vicinal methyl ramification at the distal position of oxygenated MAs, play a role in M. tuberculosis virulence in the mouse model of infection and have recently been reported to be involved in host-pathogen interplay. The migration of these compounds corresponded to that of mono- and di-ethylenic ␣-MAs (␣2⬘ and ␣3 . . .
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