S-glutathionylation-controlled apoptosis of lung epithelial cells; potential implications for lung fibrosis

HIGHLIGHTS

• who: Elizabeth Corteselli et al. from the Department of Pathology and Laboratory of Medicine, University of Vermont Larner College of Medicine, Burlington, VT, USA have published the research: S-Glutathionylation-Controlled Apoptosis of Lung Epithelial Cells; Potential Implications for Lung Fibrosis, in the Journal: Antioxidants 2022, 11, 1789. of /2022/
• how: The authors conducted a multi-omics study in airway epithelial_cells derived from WT or Glrx-/- mice stimulated with the pro-fibrotic cytokine interleukin 1 beta (IL1B) and discovered that multiple metabolic pathways were perturbed in the absence of Glrx or in response to IL1B . . .
  

   

  

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