S-nitrosylated hemoglobin predicts organ yield in neurologically-deceased human donors

HIGHLIGHTS

  • who: Ryan Nazemian from the InstitutReserve University, Cleveland, OH, USA have published the research work: S-Nitrosylated hemoglobin predicts organ yield in neurologically-deceased human donors, in the Journal: Scientific Reports Scientific Reports of 25/06/2021

SUMMARY

    Vasodilation by S-nitrosylated-Hb (SNO-Hb; i.e. release of NO bioactivity) is linked to Hb desaturation and thus provides a regulated mechanism that matches blood flow and oxygen delivery to local metabolic d ­ emand10,12. In a translational pre-clinical study utilizing swine, the authors confirmed that BD resulted in reduced circulating levels . . .

     

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