HIGHLIGHTS
- who: Antu00f3nio J. Figueira from the Federal University of Rio Janeiro, Brazil have published the article: S100B chaperone multimers suppress the formation of oligomers during Au03b242 aggregation, in the Journal: (JOURNAL)
- what: The authors demonstrate that such inhibitory behavior is a consequence of a preferential suppression of fibril catalyzed nucleation (k2 ) of Au03b242 monomers into small aggregates .
- how: For this the authors employed Au03b242 thioflavin-T (ThT) monitored aggregation assays coupled with global fitting analysis which provides information about the microscopic mechanisms accounting for the macroscopic kinetic traces . Fibril elongation the results showed . . .
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