S100b increases proliferation in pc12 neuronal cells and reduces their responsiveness to nerve growth factor via akt activation*

HIGHLIGHTS

• who: Cataldo Arcuri from the (UNIVERSITY) have published the research: S100B Increases Proliferation in PC12 Neuronal Cells and Reduces Their Responsiveness to Nerve Growth Factor via Akt Activation*, in the Journal: (JOURNAL) of November/29,/2004
• what: The authors show here that (over)expression of S100B results in enhanced cell survival under stress conditions, increased cell proliferation, a reduced extent of apoptosis, and decreased responsiveness to the differentiating effect of NGF. At present, the authors attempt to explain this discrepancy by noting that the experiments were done on PC12 cells that had been cultivated for . . .
  

   

  

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