HIGHLIGHTS
- who: John W. Hinds and collaborators from the School of Medicine at Dartmouth, Lebanon, New Hampshire, Unites States of America have published the research: S146L in MYC is a context-dependent activating substitution in cancer development, in the Journal: PLOS ONE of 11/04/2022
- what: Much of this work has been performed in the breast epithelial_cell line MCF10A. While this experiment provides robust quantitative insight into the oncogenic potential of MYC S146L, further evidence using mouse models of tumor formation may additionally support the findings and give insight in a system more recapitulative of . . .
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