Safety of beta-blocker and calcium channel blocker antihypertensive drugs in pregnancy: a mendelian randomization study

HIGHLIGHTS

  • who: Maddalena Ardissino from the Department of Epidemiology and Biostatistics, School of Public Health, PG London, UK have published the research work: Safety of beta-blocker and calcium channel blocker antihypertensive drugs in pregnancy: a Mendelian randomization study, in the Journal: (JOURNAL)
  • what: The authors identified and leveraged genetic variants that mimic BB and CCB antihypertensive drugs to investigate their effects on risk of pre-eclampsia or eclampsia, gestational diabetes and birthweight. The authors implement methods more robust to violations of the conventional Mendelian randomization assumptions: MR-Egger analysis, the weighted median method and MR . . .

     

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