Salmonella regulator stm0347 mediates flagellar phase variation via hin invertase

HIGHLIGHTS

  • who: Hongou Wang and colleagues from the Department of Microbiology, School of Basic Medical Sciences, Peking University Health Science Center have published the research: Salmonella Regulator STM0347 Mediates Flagellar Phase Variation via Hin Invertase, in the Journal: (JOURNAL) of 30/07/2022
  • what: The authors found that FliC was downregulated in the stm0347 deletion mutant compared with the wild-type (WT) strain of S. Typhimurium via proteomic profiling. The authors provide a series of lines of evidence that STM0347 might prevent invertible DNA from flipping orientation by diminishing hin mRNA levels or degrading hin DNA . . .

     

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