Salubrinal protects against cisplatin-induced cochlear hair cell endoplasmic reticulum stress by regulating eukaryotic translation initiation factor 2α signalling

HIGHLIGHTS

• who: Jincheng Zhang and Haibo Shi from the Department of Otolaryngology-Head and Neck Surgery, Jiao Tong University Affiliated Sixth People`s Hospital, China have published the research: Salubrinal Protects Against Cisplatin-Induced Cochlear Hair Cell Endoplasmic Reticulum Stress by Regulating Eukaryotic Translation Initiation Factor 2u03b1 Signalling, in the Journal: (JOURNAL)
• what: The authors focused on PERKeIF2u03b1 signalling and further investigated the role of eIF2u03b1 in cisplatin-induced ototoxicity.
• how: All experiments were conducted in accordance with the recommendations of the Constitution of the Animal Ethical and Welfare Committee. For quantification of apoptotic . . .
  

   

  

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