Salvianolic acid b activates chondrocytes autophagy and reduces chondrocyte apoptosis in obese mice via the kcnq1ot1/mir-128-3p/sirt1 signaling pathways

HIGHLIGHTS

• who: Tianwen Sun from the The degenerated cartilage tissues were obtained from the knee joints of , patients (age, u00b1, ., years) who underwent total knee arthroplasty. The normal cartilage tissues were collected from , volunteers (age,u00b1, ., years) with the femoral neck fracture with no history of rheumatoid arthritis or OA. The body mass index (BMI) of all selected patients is, ., u00b1, ., kg/m, which meets the obesity diagnostic criteria of greater than or equal to , kg/m2. These cartilage samples were immediately snap-frozen and stored in the liquid nitrogen for further experiments. The present study was approved . . .
  

   

  

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