Sarcomere dynamics revealed by a myofilament integrated fret-based biosensor in live skeletal muscle fibers

HIGHLIGHTS

• who: Ashley A. Martin from the DepartmentUniversity of have published the article: Sarcomere dynamics revealed by a myofilament integrated FRET-based biosensor in live skeletal muscle fibers, in the Journal: Scientific Reports Scientific Reports
• what: The FRET pair of Clover and mRuby2 was selected because, at the time of this study design, this fluorophore pair was superior to previously studied FRET pairs in terms of fluorescence intensity, brightness, and photostability. The authors report here the design, development, and implementation of a new skeletal muscle sarcomere activation biosensor permitting, for the first time to the knowledge . . .
  

   

  

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