Sars-cov-2-associated ssrnas activate human neutrophils in a tlr8-dependent fashion

HIGHLIGHTS

  • who: Elisa Gardiman et al. from the General Pathology Section, Department of Medicine, University of Verona, Verona, Italy have published the research work: SARS-CoV-2-Associated ssRNAs Activate Human Neutrophils in a TLR8-Dependent Fashion, in the Journal: Cells 2022, 3785 of 28/09/2022
  • what: The authors investigated whether human neutrophils respond to these SARSCoV-2 GU-rich sequences . Human neutrophils do not express TLR7 , which explains why the authors show that SCV2-RNA2 induces the release of NETs by TLR8-dependent recognition.
  • future: Obviously further studies are required to ascertain . . .

     

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