Sars-cov-2 spike protein alters microglial purinergic signaling

HIGHLIGHTS

• who: Vinu00edcius Santos Alves from the Babol University of Medical Sciences, Iran have published the research: SARS-CoV-2 Spike protein alters microglial purinergic signaling, in the Journal: (JOURNAL)
• what: The experiments were performed in triplicate, and 70-90 cells per field were evaluated in ten fields per coverslip. This study provides the first experimental evidence that SARS-CoV-2 spike_protein induces ATP secretion and alters purinergic receptors and nucleotide metabolizing enzymes in_vitro and in_vivo in microglial cells.
• how: The authors used 8-12-week-old male Swiss mice.
• future: Future . . .
  

   

  

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