Scaffold searching of fda and ema-approved drugs identi es lead candidates for drug repurposing in alzheimer ’ s disease

HIGHLIGHTS

• who: EMA-Approved Drugs Identifies Lead et al. from the Laboratory of Chemoinformatics, Infochemistry Scientific Center, ITMO, Saint-Petersburg, Russia, Department of have published the research work: Scaffold Searching of FDA and EMA-Approved Drugs Identi es Lead Candidates for Drug Repurposing in Alzheimer ’ s Disease, in the Journal: (JOURNAL)
• what: In this study, the scaffold searching approach based on known Aβ inhibitor tramiprosate to screen the DrugCentral database (n 4,642) was employed to identify hit compounds (n 13) and lead candidates (n 2) for AD drug repurposing.
• how: Sulfamazone Sulfonamide antibiotic . . .
  

   

  

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