HIGHLIGHTS
- who: Min Wang and colleagues from the (UNIVERSITY) have published the research work: Schizophrenia, amphetamine-induced sensitized state and acute amphetamine exposure all show a common alteration: increased dopamine D2 receptor dimerization, in the Journal: (JOURNAL)
- what: The aim of this study was to examine the status of D2R dimers and monomers in schizophrenia. The authors provided evidence that disruption of the D2RDAT interaction blocks amphetamine-induced up-regulation of D2R dimerization in transfected HEK293T_cells, implicating the potential role of DAT in this process.
- how: Recent data suggest that D2Rs form dimers in . . .
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