Schwann cell-derived exosomes containing mfg-e8 modify macrophage/microglial polarization for attenuating inflammation via the socs3/stat3 pathway after spinal cord injury

HIGHLIGHTS

• who: Jie Ren from the Contusion model of spinal cord injury in rats The modified Allen method was used to construct the contusion model of SCI in rats, and stability and uniformity of the model were well maintained [48]After being weighed, the rats were anesthetized with, % of isoflurane (RWD lifescience, Shenzhen, China). A dorsal laminectomy was performed on the , vertebral body to expose the spinal cord. The impact bar was placed on the spinal cord, and a , g node (the diameter of, ., mm) was freely dropped from a height of, ., cm to create contusion injury with . . .
  

   

  

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