Scican: single-cell chromatin accessibility and gene expression data integration via cycle-consistent adversarial network

HIGHLIGHTS

• who: Yang Xu from the (UNIVERSITY) have published the research: sciCAN: single-cell chromatin accessibility and gene expression data integration via cycle-consistent adversarial network, in the Journal: (JOURNAL)
• what: Considering their success in batch-effect correction, here, the authors aim to extend the use of adversarial learning to single-cell data integration across different modalities. The authors focus on modality differences and develop an improved adversarial domain adaptation approach to address multimodal data integration for chromatin accessibility (ATAC-seq) and gene_expression (RNAseq) data. The authors first benchmarked the method with 5 existing methods across . . .
  

   

  

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