Science journals — aaas

HIGHLIGHTS

• who: Daniela Ivanova et al. from the Animals Neuronal cells and brain tissue were obtained from Vamp, KO, wild-type C BL/ J mice and wild-type Sprague-Dawley rats of both sexesHorizon Discovery (St. Louis, MO, USA) generated the Vamp, KO mice on a C BL/ J background. An early stop codon was introduced by a, base pair deletion in exon , of the Vamp, gene (18009, in NC_000067.6) using CRISPR-Cas, gene editing, resulting in nonsense-mediated mRNA decay and elimination of , protein expression. For experiments, heterozygous Vamp, males and females were bred to produce . . .
  

   

  

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