Scn1a overexpression, associated with a genomic region marked by a risk variant for a common epilepsy, raises seizure susceptibility

HIGHLIGHTS

• who: Katri Silvennoinen from the SCN A expression and neuronal loss in hippocampal specimens from individuals with mesial temporal lobe epilepsy with hippocampal sclerosis We analysed SCN A mRNA expression in all available hippocampal biopsy specimens from , patients (, female have published the Article: SCN1A overexpression, associated with a genomic region marked by a risk variant for a common epilepsy, raises seizure susceptibility, in the Journal: (JOURNAL)
• what: The authors propose that quantitative precision may be important when increasing SCN1A expression in current strategies aiming to treat seizures in conditions involving SCN1A haploinsufficiency such as Dravet . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.