Scnanoatac-seq: a long-read single-cell atac sequencing method to detect chromatin accessibility and genetic variants simultaneously within an individual cell

HIGHLIGHTS

• who: Yuqiong Hu from the (UNIVERSITY) have published the article: scNanoATAC-seq: a long-read single-cell ATAC sequencing method to detect chromatin accessibility and genetic variants simultaneously within an individual cell, in the Journal: (JOURNAL) of 25/03/2022

SUMMARY

The chromatin accessibility patterns around marker genes of GM12878 cells (CD19 and CD79A) were comparable between long-read and short-read scATAC-seq (Supplementary information, Fig S2d). The authors exploited ENCODE candidate cis-regulatory elements (cCREs) to profile distributions of peaks called from NGS-based scATAC-seq data and TGS-based scNanoATAC . . .

 



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