Screening of core genes and prediction of cerna regulation mechanism of circrnas in nasopharyngeal carcinoma by bioinformatics analysis

HIGHLIGHTS

SUMMARY

Conducted numerous studies on NPC, the core genes related to NPC and their regulatory mechanisms are still poorly understood. The authors aimed to identify the hub-gene in NPC by performing the integrative analysis of Gene Expression Omnibus (GEO) and Intrinsically, circRNA can exert vital roles as a competitive endovascular RNA (ceRNA) or protein-coding RNA, or interact with RNA-binding proteins to regulate tumor development and gene_expression. The combined GEO gene_expression data and TCGA data were analyzed by WGCNA using the R language "WGCNA" package, respectively. Subsequently, the gene_expression data of tumor samples . . .

 



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