Screening of key mirnas related with the differentiation of subcutaneous adipocytes and the validation of mir-133a-3p functional significance in goats

HIGHLIGHTS

SUMMARY

Mutton flavor substances are mainly accumulated in adipose_tissue, adipocyte is the main component of adipose_tissue and adipocyte differentiation is the key process of adipose deposition. It can directly bind to important transcription factors associated with adipocyte differentiation or participate in signaling pathways that regulate cell differentiation. Researchers have identified 104 differentially expressed genes from intramuscular adipocytes in late-laying-period hens and juvenile hens by RNA-seq Integrated analysis of miRNA and genes showed that differentially expressed miRNAs/mRNAs were enriched in pathways such as ubiquitin-mediated proteolysis, the PPAR signaling pathway and other . . .

 



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