HIGHLIGHTS
- who: Mau00eftu00e9 M. Moreau and collaborators from the UnivBordeaux, INSERM, Neurocentre Magendie, , Bordeaux, France have published the research: Scribble Controls Social Motivation Behavior through the Regulation of the ERK/Mnk1 Pathway, in the Journal: Cells 2022, 11, 1601. of /2022/
- what: The authors show that Scribcrc/+ mice carrying a mutated version of Scrib displayed reduced social motivation behavior and social habituation while other behavioral domains were unaltered. This study provides evidence for the role of Scrib in the regulation of social preference and recognition, mediated by hippocampal functionality and more specifically by the ERK/Mnk . . .
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