HIGHLIGHTS
- who: Melpomeni Moustaki from the Department of Endocrinology and Diabetes Center, Hellenic Red Cross Hospital, Athens, Greece have published the article: Secondary diabetes mellitus in acromegaly, in the Journal: (JOURNAL)
- what: The authors aim to present the relationship between GH, IGF-1, insulin signaling and glucose homeostasis and how acromegaly affects it.
- future: More basic research in animal models or tissues from patients with acromegaly is required to unravel the molecular basis of insulin resistance. It would be interesting to explore how IGF-1R becomes selectively resistant as per its metabolic but not . . .
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