Secreted emc10 is upregulated in human obesity and its neutralizing antibody prevents diet-induced obesity in mice

HIGHLIGHTS

  • who: Xuanchun Wang from the Human study participants for , serum concentrations Group We included , white individuals with either leanness (BMI andlt have published the paper: Secreted EMC10 is upregulated in human obesity and its neutralizing antibody prevents diet-induced obesity in mice, in the Journal: (JOURNAL) of 21/Nov/2021
  • what: The authors demonstrate that scEMC10 is upregulated in people with obesity and is positively associated with insulin resistance. Mechanistically, the authors provide evidence that scEMC10 can be transported into cells where it binds to the catalytic subunit of PKA and inhibits its stimulatory action . . .

     

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