Secreted phospholipases a2 in hereditary angioedema with c1-inhibitor deficiency

HIGHLIGHTS

  • who: Stefania Loffredo from the Department of Translational Medical Sciences, Center for Basic and Clinical Immunology Research (CISI), University Naples, Italy have published the research work: Secreted Phospholipases A2 in Hereditary Angioedema With C1-Inhibitor Deficiency, in the Journal: (JOURNAL)
  • what: Nineteen patients were taking prophylactic therapy at the time of blood collection (4 were on tranexamic acid and 15 on attenuated androgens). in this study had C1-INH functional activity lower than 50% of normal . The authors found that plasma sPLA2 enzymatic activity and hGIIA are increased in symptom-free C1-INH-HAE patients . . .

     

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