Secreted protease prss35 suppresses hepatocellular carcinoma by disabling cxcl2-mediated neutrophil extracellular traps

HIGHLIGHTS

• who: Ting Wang from the Our research complies with all relevant ethical regulations of the University of Science and Technology of ChinaAll animal protocols , have published the paper: Secreted protease PRSS35 suppresses hepatocellular carcinoma by disabling CXCL2-mediated neutrophil extracellular traps, in the Journal: (JOURNAL)
• what: The authors show that the secreted pseudo serine protease PRSS35 functions as a tumor suppressor in HCC. Mechanistically, the authors demonstrate that active PRSS35 is processed via cleavage by proprotein convertases. Since the tumor-suppressive activity of PRSS35 appeared to depend on the in_vivo microenvironment, the authors focused the . . .
  

   

  

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